Simparica 如何發揮作用？

August 13, 2019 • ben

Simparica 如何發揮作用？

犬用 Simparica 一顆美味咀嚼錠即可快速緩解寄生蟲及其傳播的疾病，讓您和毛孩的防蟲保護輕鬆無負擔。

Simparica 是經證實可快速殺死寄生蟲的每月一次跳蚤與壁蝨治療產品。採用狗狗喜愛的美味零食形式，每顆軟嚼錠可提供長達 35 天的保護，協助您的愛犬抵禦叮咬性害蟲及其可能傳播的疾病。

與其他口服跳蚤及壁蝨治療產品一樣，犬用 Simparica 在寵物食用後會立即進入其血液循環。當跳蚤或壁蝨叮咬時，便會接觸到配方中經 FDA 核准的活性成分 sarolaner，迅速攻擊並殺死寄生蟲。僅在 3 小時內，Simparica 即可開始有效殺滅跳蚤；8 小時後，則開始殺滅包括孤星蜱、黑腳蜱、褐犬蜱、美國犬蜱及墨西哥灣沿岸蜱在內的壁蝨。Simparica 亦已證實可有效緩解及預防耳疥蟲與疥癬。其長效配方可持續控制寄生蟲長達 35 天，持續緩解寄生蟲及其傳播疾病所帶來的困擾。

Simparica 的強效成分 sarolaner 是一種殺蟲劑及殺蟎劑，會影響無脊椎動物的神經細胞功能。它藉由改變 γ-胺基丁酸（GABA）及麩胺酸受體來發揮作用，兩者皆參與神經傳導。GAGA 門控通道有助於抑制神經傳導，而 sarolaner 會干擾此機制，使跳蚤和壁蝨的神經傳導大量湧現。同時，該化合物會開啟麩胺酸門控通道，進一步加劇神經傳導的湧入。最終造成的痙攣對跳蚤和壁蝨而言是致命的；但由於 sarolaner 對無脊椎動物的作用比對哺乳動物更有效，因此 Simparica 在實地試驗中已證實對狗狗安全。

雖然極少出現不良反應，但在為期 3 個月的實地試驗中，最常見的副作用包括嘔吐、食慾下降、虛弱、嗜睡及軟便。儘管多數反應與狗狗的消化系統有關，少數個案中也出現了較嚴重的副作用，例如顫抖、肌肉抽搐及癲癇發作。Simparica 僅能憑處方取得，因此在與獸醫討論最適合您寵物的跳蚤與壁蝨治療方案時，請務必告知任何癲癇病史。

Simparica 適用於年滿 6 個月且體重至少 2.8 磅的狗狗。咀嚼錠提供各種體型狗狗適用的劑量，而且由於 Simparica 為口服投藥，無須麻煩地塗抹，也不必在幫寵物洗澡前等待。此產品尚未評估用於懷孕、配種或哺乳中的狗狗，因此這些寵物需要其他的跳蚤與壁蝨預防方案。請與您的獸醫討論 Simparica，讓您的愛犬每月享用一顆美味咀嚼錠，即可安全有效地緩解叮咬性寄生蟲的困擾。

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評論(11)

  1. Alam

    In a study, Simparica killed more brown dog ticks than NexGard. visit to know more: short.gy/kZlPAY

  2. Wendy

    Are ticks still suppost to bite your dog . I still got to pull the ticks off mine.

  3. K3anu

    Yes, the medication is absorbed from the gut to circulate in the blood. That is how it then kills the ticks/fleas after they bite and ingest blood from your dog. So the ticks will still bite but they die after. If they don't just fall off, you might still see them on your dog but most likely they are dead. The main thing is that they don't get the chance to reproduce or cause further damage to your dog.

  4. Joyce Ross

    Can my dog carry ticks on their fur to me? He is treated with simparica trio. He spends a lot of time outside and we have a real tick problem where I live

  5. Elizabeth

    Yes. My dogs have been on this for years despite never having seen a tick on them. After a ridiculously warm winter I’ve found many ticks on their fur when they come inside.

  6. Cindy

    If the tick has to bite the dog in order to be killed, how can simparica prevent tick-borne diseases, which are transmitted via tick bites?

  7. Melissa

    Does this product prevent heartworm

  8. chesney

    Simparica does not prevent heartworm, Simparica is a preventative for Flea and Tick

  9. Bill Tillchock

    I am using Simparica Trio on my Staffy Terrier. Should I not be alarmed that I am finding the remains of dead ticks on his body? I see bumps on his body which appear to have been insect bites, the remains of the insect itself. Is this evidence that Simparica is doing its job correctly? I am a new pet owner parent.

  10. Griet

    Werkt simparica trio ook tegen oormijt?

  11. chesney

    Yes, Simparica trio treats fleas, ticks, and mites.
    Ja, Simparica Trio bestrijdt vlooien, teken en mijten.

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